add directory ♦ nursing jobs ♦ physician employment
Today's News:
All Neurology Jobs
Permanent Neurology Job in Portland Oregon with Providence Health & Services
Portland, Oregon -- Providence Health & Services is seeking an excellent Stroke Neurologist to join us in an active neurological practice. Ideally seeking a Neurointensive Care Specialist; Vascular Neurologist
Permanent Neurology Job in Anchorage Alaska with Providence Health & Services
Anchorage, Alaska -- Providence Alaska Medical Center is seeking a behavioral neurologist, psychiatrist or neuropsychiatrist to join our Neuropsychiatry Services Department. Will share duties with another
Permanent Neurology Job in Walla walla Washington with Providence Health & Services
St. Mary Medical Center in Walla Walla, Washington, is seeking an outstanding neurologist specializing in EEG, and EMG to join our top-rated hospital. General practice, shared call in the community is
Archives of Neurology recent issues
NEUROLOGICAL REVIEW: Blood Protein Signature for the Early Diagnosis of Alzheimer Disease
Britschgi, M., Wyss-Coray, T. Mon, 08 Dec 2008 00:00:00 -0000
Alzheimer disease (AD) has become one of the main health concerns for the elderly population in the United States. Current treatments target symptoms only, but several advanced clinical trials are testing new drugs that are potentially disease modifying. Because AD is still difficult to diagnose in its earliest stages and the disease process is estimated to start many years before current clinical diagnosis is made, accurate and simple diagnostic tools are urgently needed. We recently described a blood-based panel of secreted signaling proteins that distinguishes between blinded samples from patients with AD and control subjects with high accuracy. The same proteins also predicted progression to AD in preclinical patients with mild cognitive impairment several years before clinical diagnosis for AD was made. Herein, we describe these findings and discuss the potential for a more general application of our proteomic approach in understanding and diagnosing disease.Published online December 8, 2008 (doi:10.1001/archneurol.2008.530).
ORIGINAL CONTRIBUTION: Heterogeneity in Response to Interferon Beta in Patients With Multiple Sclerosis: A 3-Year Monthly Imaging Study
Chiu, A. W., Richert, N., Ehrmantraut, M., Ohayon, J., Gupta, S., Bomboi, G., Gaindh, D., Cantor, F. K., Frank, J. A., McFarland, H. F., Bagnato, F. Mon, 10 Nov 2008 00:00:00 -0000
Objectives To investigate the heterogeneity in magnetic resonance image (MRI) patterns of response to interferon beta across patients with multiple sclerosis or within an individual patient over time.Design, Setting, and Patients Fifteen patients with relapsing-remitting multiple sclerosis underwent monthly MRIs and clinical examinations (6-month pretherapy phase and 36-month therapy phase) and bimonthly neutralizing antibody tests. On each MRI, the total number of contrast-enhancing lesions was noted. Therapy MRI responders were defined as those with a reduction of 60% or more in the total number of contrast-enhancing lesions during each semester of therapy.Intervention Subcutaneous administration of interferon beta-1b, 250 µg, every other day for 3 years.Main Outcome Measure Reduction in the number of contrast-enhancing lesions.Results Eight patients (53.3%) were MRI responders and 7 (46.7%) were nonresponders. Of those 7, 3 (20.0%) had only an initial optimal reduction of the total number of contrast-enhancing lesions, 2 (13.3%) never reached an optimal response, and 2 (13.3%) had a delayed optimal response. No clear association between neutralizing antibody profile and MRI response was evident.Conclusions Multiple MRI evaluations disclose that approximately only half of the patients treated with interferon beta achieve and maintain a full response to the drug over time, although an additional small number of individuals may still restore an optimal response to the drug after an initial failure.Published online November 10, 2008 (doi:10.1001/archneur.66.1.noc80047).
ABOUT THIS JOURNAL: About This Journal
Mon, 08 Dec 2008 00:00:00 -0000
Subscribe to Neurology RSS feed 
Permanent Neurology Job in Portland Oregon with Providence Health & Services
Portland, Oregon -- Providence Health & Services is seeking an excellent Stroke Neurologist to join us in an active neurological practice. Ideally seeking a Neurointensive Care Specialist; Vascular Neurologist
Permanent Neurology Job in Anchorage Alaska with Providence Health & Services
Anchorage, Alaska -- Providence Alaska Medical Center is seeking a behavioral neurologist, psychiatrist or neuropsychiatrist to join our Neuropsychiatry Services Department. Will share duties with another
Permanent Neurology Job in Walla walla Washington with Providence Health & Services
St. Mary Medical Center in Walla Walla, Washington, is seeking an outstanding neurologist specializing in EEG, and EMG to join our top-rated hospital. General practice, shared call in the community is
Archives of Neurology recent issues
NEUROLOGICAL REVIEW: Blood Protein Signature for the Early Diagnosis of Alzheimer Disease
Britschgi, M., Wyss-Coray, T. Mon, 08 Dec 2008 00:00:00 -0000
Alzheimer disease (AD) has become one of the main health concerns for the elderly population in the United States. Current treatments target symptoms only, but several advanced clinical trials are testing new drugs that are potentially disease modifying. Because AD is still difficult to diagnose in its earliest stages and the disease process is estimated to start many years before current clinical diagnosis is made, accurate and simple diagnostic tools are urgently needed. We recently described a blood-based panel of secreted signaling proteins that distinguishes between blinded samples from patients with AD and control subjects with high accuracy. The same proteins also predicted progression to AD in preclinical patients with mild cognitive impairment several years before clinical diagnosis for AD was made. Herein, we describe these findings and discuss the potential for a more general application of our proteomic approach in understanding and diagnosing disease.Published online December 8, 2008 (doi:10.1001/archneurol.2008.530).
ORIGINAL CONTRIBUTION: Heterogeneity in Response to Interferon Beta in Patients With Multiple Sclerosis: A 3-Year Monthly Imaging Study
Chiu, A. W., Richert, N., Ehrmantraut, M., Ohayon, J., Gupta, S., Bomboi, G., Gaindh, D., Cantor, F. K., Frank, J. A., McFarland, H. F., Bagnato, F. Mon, 10 Nov 2008 00:00:00 -0000
Objectives To investigate the heterogeneity in magnetic resonance image (MRI) patterns of response to interferon beta across patients with multiple sclerosis or within an individual patient over time.Design, Setting, and Patients Fifteen patients with relapsing-remitting multiple sclerosis underwent monthly MRIs and clinical examinations (6-month pretherapy phase and 36-month therapy phase) and bimonthly neutralizing antibody tests. On each MRI, the total number of contrast-enhancing lesions was noted. Therapy MRI responders were defined as those with a reduction of 60% or more in the total number of contrast-enhancing lesions during each semester of therapy.Intervention Subcutaneous administration of interferon beta-1b, 250 µg, every other day for 3 years.Main Outcome Measure Reduction in the number of contrast-enhancing lesions.Results Eight patients (53.3%) were MRI responders and 7 (46.7%) were nonresponders. Of those 7, 3 (20.0%) had only an initial optimal reduction of the total number of contrast-enhancing lesions, 2 (13.3%) never reached an optimal response, and 2 (13.3%) had a delayed optimal response. No clear association between neutralizing antibody profile and MRI response was evident.Conclusions Multiple MRI evaluations disclose that approximately only half of the patients treated with interferon beta achieve and maintain a full response to the drug over time, although an additional small number of individuals may still restore an optimal response to the drug after an initial failure.Published online November 10, 2008 (doi:10.1001/archneur.66.1.noc80047).
ABOUT THIS JOURNAL: About This Journal
Mon, 08 Dec 2008 00:00:00 -0000

Sites:
Family Practice Notebook: Neurology: Covers Autonomic, Cerebellum, Chorea, Cranial Nerve, Cognitive, CSF, Demyelinating, Disability, Examination, Headache, Level of Consciousness, Motor, Procedure, Seizure, Sensory, Symptom Evaluation and Tremor. Related chapters from other specialties include Cardiovascular, Dermatology, Ophthalmo...Foundation for Education and Research in Neurological Emergencies: Information about this non-profit organization for improving the care of Emergency Department patients with neurological emergencies. Offers free educational courses and sponsors research for Emergency Physicians.
General Practice Notebook - Neurology: Coverage of this medical specialty.
HowStuffWorks: How Your Brain Works: Every animal you can think of -- mammals, birds, reptiles, fish, amphibians -- all have brains. But the human brain is unique. It gives us the power to think, plan, speak, imagine... Find out all about this amazing organ.
Institute for Nerve Medicine: Presenting information on disorders of the cranial, spinal and peripheral nerves. Includes illustrated descriptions of treatment options.
Iowa Neuroradiology Library: Department of Neurology, University of Iowa Hospitals and Clinics. Radiology teaching file.
National Institute of Neurological Disorders and Stroke: An NIH site with research and clinical information on disorders of the brain and nervous system.
Neuroconsult: Information resource on Clinical Neurology. Covering areas such as alzheimers, epilepsy, migraine, motor neurone, multiple sclerosis, pain, parkinsons, schizophrenia, and stroke.
NeuroExam.com: neuroexam.com is an interactive online guide to the neurologic examination, with video demonstrations. It is a companion to 'The NeuroExam Video' and 'Neuroanatomy Through Clinical Cases', both by Hal Blumenfeld
Neurological Teaching Videos: Digital video of the neurologic exam [Online registration, (free) required] by Wright State University.
Neurology Channel: NeurologyChannel is a comprehensive resource for seizures, stroke, coma, Alzheimer's, headaches, migraines, Parkinson's, and other brain and nervous system disorders. Features patient forum and neurologist search.
Neurology in Clinical Practice, 3e: An online professional neurology reference.
Neurology Jobs: Physician employment opportunities for all specialties in North America.
Neurology-Info.net: Information about the nervous system in health and disease. Part of the ALtruis Biomedical Network.
NeurologyLinx: Neurologist keep current with free medical news and daily newsletters. NeurologyLinx and MDLinx aggregates the most current medical journal news and research from premier medical and healthcare journals and news sources. Comprehensive, specialized content updated every day on the web and in email...
Neurosciences on the Internet: Neurosciences on the Internet contains a searchable and browsable index of neuroscience resources available on the World Wide Web and other parts of the Internet. Neurobiology, neurology, neurosurgery, psychiatry, psychology, cognitive science sites and information on human neurological diseases...
Oregon Nerve Center: The Oregon Nerve Center is a leading center for research in the field of neurology.
